If you or your child suffers from allergies, your doctor or pharmacist may recommend a medicine called DESELEX®. This medication helps manage symptoms like sneezing, runny nose, itchy eyes, and even hives. But DESELEX® comes in two forms: syrup and tablets. Which one is better for you or your child? This guide explains everything in clear, simple language to help you understand and compare both options.
What is DESELEX®?
DESELEX® is an anti-allergy medicine. Its active ingredient is desloratadine, which belongs to a group of medicines called antihistamines. These medicines help reduce allergy symptoms by blocking a natural substance in your body called histamine.
DESELEX® comes in two main forms:
- DESELEX® Syrup: Contains 2.5 mg of desloratadine in every 5 ml of syrup.
- DESELEX® Tablets: Each tablet contains 5 mg of desloratadine.
DESELEX® Syrup Ingredients:
- Active Ingredient: Desloratadine (2.5 mg per 5 ml)
- Sweeteners: Sorbitol (12%), Sucrose (40%)
- Other Ingredients: Disodium edetate, citric acid, propylene glycol, sodium citrate, bubble gum flavour, dye (FD & C no. 6), purified water
- Preservative: Sodium benzoate (0.1%)
DESELEX® Tablet Ingredients:
- Active Ingredient: Desloratadine (5 mg per tablet)
- Other Ingredients: Calcium phosphate, maize starch, microcrystalline cellulose, talc, purified water
- Sugar: Lactose monohydrate
What Is It Used For?
Both DESELEX® syrup and tablets are used to treat:
- Allergic rhinitis: This includes symptoms like sneezing, runny or itchy nose, and itchy or watery eyes. It can be seasonal (like hay fever) or year-round.
- Chronic idiopathic urticaria: A condition that causes itching, redness, and hives (rash or bumps on the skin).
How to Take DESELEX®
| Age Group | DESELEX® Syrup Dosage | DESELEX® Tablet Dosage |
|---|---|---|
| Children 2 to 5 years | 2.5 ml (1.25 mg) once daily | Not recommended |
| Children 6 to 11 years | 5 ml (2.5 mg) once daily | Not recommended |
| 12 years and older | 10 ml (5 mg) once daily | 1 tablet (5 mg) once daily |
- Both forms can be taken with or without food.
- Always follow your doctor’s instructions.
Duration of Use:
- Allergic Rhinitis: Up to 4 weeks
- Chronic Urticaria: Up to 6 weeks
Who Should Not Take DESELEX®?
Avoid DESELEX® if you:
- Are allergic to desloratadine or any of the ingredients.
- Are under 2 years old (for syrup).
- Are under 12 years old (for tablets).
- Have a rare condition that affects sugar digestion (for tablet users).
Speak to your doctor before using DESELEX® if you:
- Have liver or kidney problems.
- Have a history of seizures.
- Are pregnant or breastfeeding.
Possible Side Effects
| Body System | Possible Side Effects (Syrup & Tablet) |
|---|---|
| Immune System | Allergic reactions, swelling, rash |
| Nervous System | Drowsiness, dizziness, headache, insomnia, seizures |
| Heart | Fast heartbeat, palpitations |
| Digestive System | Nausea, vomiting, stomach pain, dry mouth, diarrhea |
| Liver | Hepatitis, abnormal liver tests, increased bilirubin |
| Muscles | Muscle pain |
| General | Fatigue (feeling tired) |
| Others | Increased appetite |
Note: Not everyone will experience these side effects. Always consult a healthcare professional if you notice anything unusual.
Warnings and Precautions
- Driving or using machinery: While desloratadine usually doesn’t cause drowsiness, some people may feel sleepy. If that happens, avoid driving or using machines.
- Drug interactions: Tell your doctor about all medications you are taking, especially:
- Antifungals like ketoconazole
- Antibiotics like erythromycin and azithromycin
- Antidepressants like fluoxetine
- Acid-reducing meds like cimetidine
DESELEX® In Case of Pregnancy
DESELEX® is not recommended for use during pregnancy. Although animal studies haven’t shown harmful effects, there isn’t enough information about its safety in human pregnancies. Because of this, doctors advise avoiding it during pregnancy unless the benefits clearly outweigh the risks.
Important: Always talk to your doctor before taking any medicine while pregnant — even over-the-counter ones.
Why Should DESELEX® Be Avoided During Pregnancy?
- There’s not enough research to say it’s completely safe.
- DESELEX® contains desloratadine, which can cross into the bloodstream and might reach the baby.
- Even though no harmful effects were seen in animal tests, humans might react differently.
What If You Accidentally Took DESELEX® While Pregnant?
Don’t panic. One accidental dose is unlikely to harm you or your baby. But you should still:
- Tell your doctor or midwife.
- Let them know how much you took and when.
- Follow their advice for what to do next.
Can I Take DESELEX® While Trying to Get Pregnant?
It’s best to avoid it while trying to conceive, unless your doctor says it’s okay.
Are There Safer Alternatives for Pregnant Women With Allergies?
Yes, some allergy medicines are considered safer during pregnancy. Your doctor might recommend:
Safer Allergy Medicines for Pregnant Women in South Africa
Yes, some allergy treatments are considered safer during pregnancy, even in South Africa. While DESELEX® (desloratadine) is not recommended, doctors may suggest safer options that are widely available locally.
✅ Safer Alternatives Commonly Used in South Africa:
| Medicine / Treatment | Availability in South Africa | Use in Pregnancy |
|---|---|---|
| Loratadine (e.g., Loratyn, Clarityne) | OTC or pharmacy medicine | Usually considered safe in all trimesters |
| Cetirizine (e.g., Texa, Zyrtec) | Available at pharmacies | Often used under medical supervision |
| Nasal saline sprays (e.g., Sterimar, Salex) | Widely available at pharmacies and stores | 100% safe, no medication involved |
| Steam inhalation | Home remedy | Safe and effective for congestion relief |
🩺 Always consult your doctor or pharmacist before starting any new medication — even if it’s considered “safe” during pregnancy.
📝 Notes for South African Women:
- Clarityne and Loratyn are trusted loratadine brands in SA.
- Texa is a popular cetirizine brand that some doctors recommend during pregnancy.
- Salex® is a common, drug-free nasal spray available at Dis-Chem, Clicks, and other major retailers.
- Avoid self-medicating. Pregnant women should always be cautious with over-the-counter medicines.
DESELEX® and Breastfeeding
DESELEX® should also be avoided while breastfeeding. That’s because:
- Desloratadine can pass into breast milk.
- It’s not clear how it may affect your baby.
- Doctors usually advise against using it unless absolutely necessary.
If you’re breastfeeding and need allergy relief, safer options might include:
- Non-sedating antihistamines (like loratadine or cetirizine) in low doses
- Natural remedies, such as saline sprays or steam therapy
Storage Instructions
- Store below 30°C in the original container.
- Do not refrigerate or keep in a bathroom.
- Keep away from children.
- Do not use after expiry date.
- Return unused medicine to your pharmacy.
Special Notes on Ingredients
- Syrup: Contains sucrose and sorbitol. People with sugar intolerance should consult a doctor before use.
- Tablet: Contains lactose. Not suitable for people with lactose intolerance.
How Fast Does It Work?
- Many users feel symptom relief within 1 to 2 hours of taking DESELEX®.
- The effects last for a full 24 hours, making it convenient for once-a-day use.
Pharmacological Insights (Simple Explanation)
Desloratadine works by blocking histamine – the chemical in your body that causes allergy symptoms. Unlike older antihistamines, it does not usually make you sleepy.
Desloratadine starts working within 30 minutes, reaches its peak in about 3 hours, and stays active for around 27 hours. It binds to proteins in your blood and doesn’t build up too much over time.
Summary Comparison Table
| Feature | DESELEX® Syrup | DESELEX® Tablets |
|---|---|---|
| Form | Liquid syrup | Film-coated tablet |
| Active Ingredient | 2.5 mg per 5 ml | 5 mg per tablet |
| Sugar Content | Contains sucrose and sorbitol | Contains lactose |
| Suitable for Kids | Yes, from 2 years old | Only from 12 years old |
| Dosing | 2.5 ml – 10 ml daily (based on age) | 1 tablet daily (12+ years) |
| Taste | Bubble gum flavor, kid-friendly | No flavor |
| Best For | Children and people who struggle with pills | Teens and adults who prefer tablets |
| Common Side Effects | Headache, dry mouth, fatigue | Headache, nausea, fatigue |
| Sedative Effect | Rare | Rare |
| Prescription Needed? | May vary by country | May vary by country |
Final Thoughts
Both DESELEX® syrup and tablets are effective for treating allergy symptoms like hay fever and hives. The best choice depends on your age, medical history, and personal preference:
- Choose DESELEX® syrup for young children or if you prefer a flavored liquid.
- Choose DESELEX® tablets if you are 12 or older and prefer a quick, no-fuss tablet.
As always, talk to your doctor or pharmacist before starting any medication. They can help you choose the right form and dose for your specific needs.
Stay allergy-free and breathe easier with DESELEX®
Education:
Maria Shkarletova Kupyanskiy Medical College 2008-2012
NPU (National Pharmaceutical University) 2013-2018
Work experience:
2012 – 2014 Center for Emergency Medical Care and Catastrophe Medicine. Regional Perinatal Center – Midwife
2014 – 2015 Titan TPO Health Pharmacy – Pharmacist
2015 – 2016 FOP Kravchenko – Pharmacist
2016 – 2018 FOP Kravchenko Pharmacy – Pharmacist
2018 – to date FOP Sanders Loft (Wholesale Pharmacy) – Pharmacist
