{"id":1140,"date":"2025-05-26T21:32:14","date_gmt":"2025-05-26T19:32:14","guid":{"rendered":"https:\/\/rxquora.com\/en\/?p=1140"},"modified":"2025-09-21T19:27:19","modified_gmt":"2025-09-21T17:27:19","slug":"clopamon-injection-uses-side-effects","status":"publish","type":"post","link":"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/","title":{"rendered":"Clopamon Injection:Uses, Safety Instructions And Side Effect"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">CLOPAMON Injection 10 mg\/2 ml is a powerful and reliable medication used primarily to treat nausea, vomiting, and certain gastrointestinal conditions. Its active ingredient, metoclopramide, is known for its dual action on the digestive system and central nervous system, providing symptomatic relief in a variety of clinical settings.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_Scheduling_Status\"><\/span>1. Scheduling Status<span class=\"ez-toc-section-end\"><\/span><\/h2><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#1_Scheduling_Status\" >1. Scheduling Status<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#2_Proprietary_Name_and_Dosage_Form\" >2. Proprietary Name and Dosage Form<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#3_Composition\" >3. Composition<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#4_Category_and_Class\" >4. Category and Class<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#5_CLOPAMON_Injection_Uses\" >5. CLOPAMON Injection Uses<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Pharmacodynamic_Properties\" >Pharmacodynamic Properties<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Gastrointestinal_Action\" >Gastrointestinal Action<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Gastro-Oesophageal_Junction\" >Gastro-Oesophageal Junction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Effect_of_Anticholinergics\" >Effect of Anticholinergics<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Anti-Emetic_Action\" >Anti-Emetic Action<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Other_Actions\" >Other Actions<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#6_Indications\" >6. Indications<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Digestive_Disorders\" >Digestive Disorders<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Nausea_and_Vomiting\" >Nausea and Vomiting<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Diagnostic_Radiology\" >Diagnostic Radiology<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Duodenal_Intubation\" >Duodenal Intubation<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#7_Contraindications\" >7. Contraindications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#8_Warnings_and_Special_Precautions\" >8. Warnings and Special Precautions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#9_Interactions\" >9. Interactions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#10_Human_Reproduction\" >10. Human Reproduction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#11_Dosage_and_Directions_for_Use\" >11. Dosage and Directions for Use<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Parenteral_Administration\" >Parenteral Administration<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#For_Diagnostic_Radiology\" >For Diagnostic Radiology<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#12_Side_Effects\" >12. Side Effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Common_Reactions\" >Common Reactions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Rare_and_Serious_Reactions\" >Rare and Serious Reactions<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-27\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#13_Known_Symptoms_of_Overdosage_and_Treatment\" >13. Known Symptoms of Overdosage and Treatment<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-28\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Symptoms_of_Overdose\" >Symptoms of Overdose<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-29\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Treatment\" >Treatment<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-30\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#14_Identification\" >14. Identification<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-31\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#15_Presentation\" >15. Presentation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-32\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#16_Storage_Instructions\" >16. Storage Instructions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-33\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#17_Name_and_Business_Address_of_the_Holder_of_the_Certificate_of_Registration\" >17. Name and Business Address of the Holder of the Certificate of Registration<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-34\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/#Final_Thoughts\" >Final Thoughts<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON Injection falls under <strong>Schedule 4 (S4)<\/strong>, which means it is a prescription-only medicine. It should be used under the supervision of a qualified healthcare provider.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_Proprietary_Name_and_Dosage_Form\"><\/span>2. Proprietary Name and Dosage Form<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Brand Name:<\/strong> CLOPAMON INJECTION<\/li>\n\n\n\n<li><strong>Strength:<\/strong> 10 mg of metoclopramide per 2 ml<\/li>\n\n\n\n<li><strong>Form:<\/strong> Clear, colorless injectable liquid<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This medication is supplied in ampoules for intramuscular (IM) or intravenous (IV) use.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_Composition\"><\/span>3. Composition<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Each 2 ml ampoule of CLOPAMON Injection contains:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Component<\/strong><\/th><th><strong>Quantity<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Metoclopramide<\/td><td>10 mg<\/td><\/tr><tr><td>Sodium chloride<\/td><td>As excipient<\/td><\/tr><tr><td>Water for injection<\/td><td>As excipient<\/td><\/tr><tr><td>Sugar<\/td><td><strong>Free<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">The formulation is isotonic and stable when administered as intended. It must not be diluted before injection.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_Category_and_Class\"><\/span>4. Category and Class<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON belongs to:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Category:<\/strong> A 5.7.2<\/li>\n\n\n\n<li><strong>Pharmacological Class:<\/strong> Anti-emetics and antivertigo preparations<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">It is primarily used to control nausea, vomiting, and gastrointestinal motility issues.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_CLOPAMON_Injection_Uses\"><\/span>5. CLOPAMON Injection Uses<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON Injection works through multiple mechanisms, offering both gastrointestinal and anti-emetic benefits.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pharmacodynamic_Properties\"><\/span>Pharmacodynamic Properties<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Gastrointestinal_Action\"><\/span>Gastrointestinal Action<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Metoclopramide stimulates the digestive tract by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Increasing the frequency and strength of antral (stomach) contractions<\/li>\n\n\n\n<li>Enhancing duodenal motility<\/li>\n\n\n\n<li>Accelerating gastric emptying<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This action makes CLOPAMON useful in treating conditions involving delayed stomach emptying and gastrointestinal stasis.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Gastro-Oesophageal_Junction\"><\/span>Gastro-Oesophageal Junction<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">It increases pressure at the cardiac sphincter, helping to prevent acid reflux and regurgitation. This effect is more pronounced in individuals with normal resting sphincter pressure.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Effect_of_Anticholinergics\"><\/span>Effect of Anticholinergics<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Anticholinergic medications like atropine can diminish the gastrointestinal effects of CLOPAMON if taken within three hours of administration.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Anti-Emetic_Action\"><\/span>Anti-Emetic Action<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON works centrally by acting on the chemoreceptor trigger zone (CTZ) in the brain to suppress nausea and vomiting. This action remains effective even in the presence of anticholinergic medications.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Other_Actions\"><\/span>Other Actions<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Metoclopramide also stimulates <strong>prolactin secretion<\/strong>, which may lead to hormonal <a href=\"https:\/\/rxquora.com\/en\/donapan-tablet\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/donapan-tablet\/\">side effects<\/a> in some users.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"6_Indications\"><\/span>6. Indications<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON Injection is used in the following clinical situations:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Digestive_Disorders\"><\/span>Digestive Disorders<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Post-vagotomy syndrome<\/li>\n\n\n\n<li>Conditions associated with delayed gastric emptying or hypomotility<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Nausea_and_Vomiting\"><\/span>Nausea and Vomiting<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Effective in controlling nausea and vomiting caused by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Medications<\/li>\n\n\n\n<li>Kidney failure (uraemia)<\/li>\n\n\n\n<li>Cancer<\/li>\n\n\n\n<li>Gastrointestinal disorders<\/li>\n\n\n\n<li>Post-anaesthetic recovery<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diagnostic_Radiology\"><\/span>Diagnostic Radiology<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Improves visualization during imaging studies by:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Use Case<\/strong><\/th><th><strong>Purpose<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Delayed barium meal studies<\/td><td>Reduces spasm in the duodenal cap<\/td><\/tr><tr><td>Hypotonic stomach (gastric stasis)<\/td><td>Enhances emptying and visual clarity<\/td><\/tr><tr><td>Preventing vomiting during barium exams<\/td><td>Reduces risk of emesis in sensitive patients<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Duodenal_Intubation\"><\/span>Duodenal Intubation<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Facilitates gastrointestinal procedures by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Promoting gastric emptying<\/li>\n\n\n\n<li>Reducing nausea and gag reflexes<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"7_Contraindications\"><\/span>7. Contraindications<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON should <strong>not<\/strong> be used in the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Gastrointestinal bleeding, obstruction, or perforation<\/li>\n\n\n\n<li>Immediately post-operative GI surgery<\/li>\n\n\n\n<li>Phaeochromocytoma (risk of hypertensive crisis)<\/li>\n\n\n\n<li>Epilepsy (risk of seizures)<\/li>\n\n\n\n<li>Porphyria<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Use is also discouraged in scenarios where increased gastrointestinal motility could be dangerous.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"8_Warnings_and_Special_Precautions\"><\/span>8. Warnings and Special Precautions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pregnancy:<\/strong> Safety is not established. Use only if absolutely necessary.<\/li>\n\n\n\n<li><strong>Children and Elderly:<\/strong> Higher risk of extrapyramidal symptoms. Caution is advised.<\/li>\n\n\n\n<li><strong>Renal or Hepatic Impairment:<\/strong> Risk of fluid retention and toxicity; monitor closely.<\/li>\n\n\n\n<li><strong>Dilution Warning:<\/strong> Do not dilute ampoules as it affects isotonicity and drug stability.<\/li>\n\n\n\n<li><strong>Long-Term Use:<\/strong> Requires regular medical review.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"9_Interactions\"><\/span>9. Interactions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"690\" height=\"388\" src=\"https:\/\/rxquora.com\/en\/wp-content\/uploads\/2025\/05\/Clopamon-Injection-Uses-Safety-Instructions-And-Side-Effect-1.jpeg\" alt=\"Clopamon Injection Uses, Safety Instructions And Side Effect and more\" class=\"wp-image-1264\" srcset=\"https:\/\/rxquora.com\/en\/wp-content\/uploads\/2025\/05\/Clopamon-Injection-Uses-Safety-Instructions-And-Side-Effect-1.jpeg 690w, https:\/\/rxquora.com\/en\/wp-content\/uploads\/2025\/05\/Clopamon-Injection-Uses-Safety-Instructions-And-Side-Effect-1-300x169.jpeg 300w\" sizes=\"(max-width: 690px) 100vw, 690px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON can interact with several medications:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Interacting Substance<\/strong><\/th><th><strong>Effect<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Phenothiazines<\/td><td>Increased risk of extrapyramidal reactions<\/td><\/tr><tr><td>Lithium<\/td><td>Increased toxicity<\/td><\/tr><tr><td>Antidepressants &amp; antiepileptics<\/td><td>Caution due to central nervous system effects<\/td><\/tr><tr><td>Antimuscarinics &amp; opioids<\/td><td>Reduce CLOPAMON&#8217;s GI effects<\/td><\/tr><tr><td>Digoxin<\/td><td>Reduced stomach absorption<\/td><\/tr><tr><td>Aspirin, Paracetamol<\/td><td>Increased small intestine absorption<\/td><\/tr><tr><td>Suxamethonium<\/td><td>Prolonged neuromuscular blockade<\/td><\/tr><tr><td>Bromocriptine<\/td><td>Reduced effectiveness due to raised prolactin levels<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"10_Human_Reproduction\"><\/span>10. Human Reproduction<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pregnancy:<\/strong> Not established as safe.<\/li>\n\n\n\n<li>Use during pregnancy only when clearly needed and under professional guidance.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"11_Dosage_and_Directions_for_Use\"><\/span>11. Dosage and Directions for Use<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Parenteral_Administration\"><\/span>Parenteral Administration<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Age Group<\/strong><\/th><th><strong>Dosage<\/strong><\/th><th><strong>Route<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Adults &amp; Children &gt;14 yrs<\/td><td>10 mg (1 ampoule), 1\u20133 times daily<\/td><td>IV or IM<\/td><\/tr><tr><td>Children 5\u201314 yrs<\/td><td>2.5 mg (0.5 ml of ampoule), twice daily<\/td><td>IV or IM<\/td><\/tr><tr><td>Children 3\u20135 yrs<\/td><td>1 mg (0.2 ml), twice daily<\/td><td>IV or IM<\/td><\/tr><tr><td>Children 1\u20133 yrs<\/td><td>0.5 mg (0.1 ml), twice daily<\/td><td>IV or IM<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Children&#8217;s doses should be given using a tuberculin syringe for accuracy.<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"For_Diagnostic_Radiology\"><\/span>For Diagnostic Radiology<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Route<\/strong><\/th><th><strong>Dose<\/strong><\/th><th><strong>Timing Before Procedure<\/strong><\/th><\/tr><\/thead><tbody><tr><td>IV<\/td><td>10\u201320 mg (1\u20132 ampoules)<\/td><td>5\u201315 minutes before barium meal<\/td><\/tr><tr><td>IM<\/td><td>10\u201320 mg<\/td><td>10\u201315 minutes before barium meal<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"12_Side_Effects\"><\/span>12. Side Effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON may cause various side effects, especially during prolonged use or in vulnerable populations.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Common_Reactions\"><\/span>Common Reactions<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Extrapyramidal symptoms (more common in young females)<\/li>\n\n\n\n<li>Restlessness, dizziness, drowsiness, and headaches<\/li>\n\n\n\n<li>Gastrointestinal upsets like diarrhea<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Rare_and_Serious_Reactions\"><\/span>Rare and Serious Reactions<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Condition<\/strong><\/th><th><strong>Description<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Parkinsonism, tardive dyskinesia<\/td><td>Usually in elderly or prolonged use<\/td><\/tr><tr><td>Hypotension\/Hypertension<\/td><td>Blood pressure changes<\/td><\/tr><tr><td>Depression<\/td><td>Mood-related <a href=\"https:\/\/rxquora.com\/en\/relislim-uses-side-effects-precautions-and-more\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/relislim-uses-side-effects-precautions-and-more\/\">side effects<\/a><\/td><\/tr><tr><td>Blood disorders<\/td><td>Rare blood count abnormalities<\/td><\/tr><tr><td>Hypersensitivity reactions<\/td><td>Allergic responses<\/td><\/tr><tr><td>Neuroleptic malignant syndrome<\/td><td>Life-threatening, rare reaction<\/td><\/tr><tr><td>Urinary incontinence<\/td><td>Uncontrolled urination<\/td><\/tr><tr><td>Hormonal effects (galactorrhoea)<\/td><td>Due to prolactin stimulation<\/td><\/tr><tr><td>Raised aldosterone levels<\/td><td>Temporary hormonal imbalance<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"13_Known_Symptoms_of_Overdosage_and_Treatment\"><\/span>13. Known Symptoms of Overdosage and Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Symptoms_of_Overdose\"><\/span>Symptoms of Overdose<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Overdose may lead to:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dyskinetic reactions<\/li>\n\n\n\n<li>Muscle spasms (especially of the face and neck)<\/li>\n\n\n\n<li>Tongue protrusion<\/li>\n\n\n\n<li>In severe cases: <strong>opisthotonos<\/strong> (severe body arching)<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Treatment\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Treatment involves administering <strong>anti-Parkinson drugs<\/strong> such as <strong>procyclidine<\/strong> to counteract movement disorders.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"14_Identification\"><\/span>14. Identification<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Appearance: <strong>Clear, colorless liquid<\/strong><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"15_Presentation\"><\/span>15. Presentation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON Injection is packaged as follows:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>1 x 2 ml ampoule<\/strong> per unit<\/li>\n\n\n\n<li><strong>10 ampoules<\/strong> per pack, supplied in a polystyrene container<\/li>\n\n\n\n<li>Includes patient information leaflet<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"16_Storage_Instructions\"><\/span>16. Storage Instructions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Storage Parameter<\/strong><\/th><th><strong>Requirement<\/strong><\/th><\/tr><\/thead><tbody><tr><td>Temperature<\/td><td>Store at or below 25 \u00b0C<\/td><\/tr><tr><td>Light<\/td><td>Protect from light<\/td><\/tr><tr><td>Packaging<\/td><td>Keep in original packaging<\/td><\/tr><tr><td>Discoloration<\/td><td>Discard ampoules that appear yellow<\/td><\/tr><tr><td>Safety<\/td><td>Keep out of reach of children<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"17_Name_and_Business_Address_of_the_Holder_of_the_Certificate_of_Registration\"><\/span>17. Name and Business Address of the Holder of the Certificate of Registration<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Pharmacare Limited<\/strong><br>Healthcare Park, Woodlands Drive<br>Woodmead 2191, South Africa<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Final_Thoughts\"><\/span>Final Thoughts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CLOPAMON Injection 10 mg\/2 ml is a versatile, clinically trusted medication with multiple uses across gastroenterology, radiology, and post-operative care. However, due to the potential for serious <a href=\"https:\/\/rxquora.com\/en\/alcophyllexuses-side-effects-precautions-and-more\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/alcophyllexuses-side-effects-precautions-and-more\/\">side effects<\/a>, it should only be used under appropriate medical supervision. Patients and healthcare providers must be vigilant about dosage, contraindications, and possible interactions to ensure <a href=\"https:\/\/rxquora.com\/en\/histacon-capsules-uses-side-effects-and-safe-use-guide\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/histacon-capsules-uses-side-effects-and-safe-use-guide\/\">safe and effective treatment<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you\u2019re considering this medication or have been prescribed CLOPAMON, consult your healthcare provider for detailed guidance tailored to your medical history.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sources: <a href=\"https:\/\/www.sahpra.org.za\/wp-content\/uploads\/2020\/05\/CLOPAMON_PI_Aspen-Pharmacare_MCC-Format_10.11.1981.pdf\" data-type=\"link\" data-id=\"https:\/\/www.sahpra.org.za\/wp-content\/uploads\/2020\/05\/CLOPAMON_PI_Aspen-Pharmacare_MCC-Format_10.11.1981.pdf\" rel=\"nofollow noopener\" target=\"_blank\">SAHPRA<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n","protected":false},"excerpt":{"rendered":"<p>CLOPAMON Injection 10 mg\/2 ml is a powerful and reliable medication used primarily to treat nausea, vomiting, and certain gastrointestinal conditions. Its active ingredient, metoclopramide, is known for its dual action on the digestive system and central nervous system, providing symptomatic relief in a variety of clinical settings. 1. Scheduling Status CLOPAMON Injection falls under &#8230; <a title=\"Clopamon Injection:Uses, Safety Instructions And Side Effect\" class=\"read-more\" href=\"https:\/\/rxquora.com\/en\/clopamon-injection-uses-side-effects\/\" aria-label=\"Read more about Clopamon Injection:Uses, Safety Instructions And Side Effect\">Read more<\/a><\/p>\n","protected":false},"author":6,"featured_media":1263,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-1140","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gastritis"],"_links":{"self":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/posts\/1140","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/comments?post=1140"}],"version-history":[{"count":0,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/posts\/1140\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/media\/1263"}],"wp:attachment":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/media?parent=1140"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/categories?post=1140"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/tags?post=1140"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}