{"id":2084,"date":"2025-09-24T20:01:13","date_gmt":"2025-09-24T18:01:13","guid":{"rendered":"https:\/\/rxquora.com\/en\/?p=2084"},"modified":"2025-09-24T20:01:17","modified_gmt":"2025-09-24T18:01:17","slug":"peploc-otc-uses-side-effects-warnings-precautions","status":"publish","type":"post","link":"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/","title":{"rendered":"PEPLOC OTC:Uses,Side Effects,Warnings,Precautions"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>It<\/strong> is an acid-reducing medicine in tablet form. It is scheduled as <strong>S2<\/strong> in South Africa and is supplied without a doctor\u2019s prescription for <strong>short-term, temporary relief of heartburn and hyperacidity<\/strong>. Treatment is limited to <strong>one 20 mg tablet once daily<\/strong> for <strong>a maximum of 14 days<\/strong>. If your symptoms persist or get worse, you must speak to a health care professional.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_it_is_and_what_it_is_used_for\"><\/span>What it is and what it is used for<span class=\"ez-toc-section-end\"><\/span><\/h2><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#What_it_is_and_what_it_is_used_for\" >What it is and what it is used for<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#How_it_works\" >How it works<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Who_should_NOT_use_this_medicine\" >Who should NOT use this medicine<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Warnings_and_precautions_Read_before_use\" >Warnings and precautions (Read before use)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Pregnancy_planning_pregnancy_and_breastfeeding\" >Pregnancy, planning pregnancy, and breastfeeding<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Interactions\" >Interactions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#How_to_take_Step-by-step\" >How to take (Step-by-step)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Dosing_table\" >Dosing table<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Possible_side_effects\" >Possible side effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Serious%E2%80%94seek_urgent_help\" >Serious\u2014seek urgent help<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Common\" >Common<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Less_common\" >Less common<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Other\" >Other<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Storage_and_disposal\" >Storage and disposal<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#What_the_medicine_contains\" >What the medicine contains<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Pack_information_and_appearance\" >Pack information and appearance<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/#Practical_FAQs\" >Practical FAQs<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Active ingredient and class<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pantoprazole<\/strong> is a <strong>proton pump inhibitor (PPI)<\/strong>. PPIs reduce the amount of acid produced in the stomach.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Indications\/uses <\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Temporary short-term relief of heartburn and hyperacidity<\/strong>.<\/li>\n\n\n\n<li>The <strong>maximum daily dose is 20 mg<\/strong>, and the <strong>maximum treatment period is 14 days<\/strong>.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_it_works\"><\/span>How it works <span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pantoprazole acts on acid-producing cells in the stomach and <strong>turns down the \u201cacid pump\u201d<\/strong>, lowering the amount of acid released. Less acid can help ease <strong>burning<\/strong> and <strong>discomfort<\/strong> related to heartburn and hyperacidity.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_should_NOT_use_this_medicine\"><\/span>Who should NOT use this medicine<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Do <strong>not<\/strong> take PEPLOC OTC if any of the following apply:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>You are <strong>allergic<\/strong> (hypersensitive) to <strong>pantoprazole<\/strong> or any ingredient in the tablet.<\/li>\n\n\n\n<li>You have <strong>impaired liver function<\/strong> or <strong>liver disease<\/strong>.<\/li>\n\n\n\n<li>You are <strong>taking atazanavir<\/strong> (used in the treatment of HIV).<\/li>\n\n\n\n<li>It is for a <strong>child<\/strong> (safety and efficacy in children have not been established).<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Stop and speak to a health care professional first<\/strong> if you are unsure about any of the above.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Warnings_and_precautions_Read_before_use\"><\/span>Warnings and precautions (Read before use)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Before using PEPLOC OTC, speak to your doctor or pharmacist if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Kidney problems:<\/strong> use with care if you have <strong>impaired kidney function<\/strong>.<\/li>\n\n\n\n<li><strong>Blood-thinning treatment:<\/strong> if you take <strong>warfarin<\/strong> (a medicine that reduces blood clotting), your health care provider may need to <strong>monitor clotting<\/strong>.<\/li>\n\n\n\n<li><strong>Liver disease:<\/strong> discuss with your health care provider.<\/li>\n\n\n\n<li><strong>Low magnesium (hypomagnesaemia):<\/strong> caution if you currently have, or are at risk of, <strong>low magnesium<\/strong>.<\/li>\n\n\n\n<li><strong>Stomach malignancy (cancer\/tumour):<\/strong> additional caution if you are being treated for, or have a <strong>history of<\/strong>, malignancies in the <strong>stomach area<\/strong>.<\/li>\n\n\n\n<li><strong>Vitamin B12 deficiency:<\/strong> tell your health care provider if you have a <strong>history of B12 deficiency<\/strong>.<\/li>\n\n\n\n<li><strong>Persistent diarrhoea:<\/strong> if you develop <strong>diarrhoea that does not improve<\/strong>, contact your doctor or health care professional as soon as possible.<\/li>\n\n\n\n<li><strong>Bone health and age:<\/strong> if you are <strong>over 50 years of age<\/strong> or take PEPLOC <strong>for a long period or in high doses<\/strong>, it <strong>may cause low magnesium<\/strong> and <strong>increase the risk of bone fractures<\/strong> in the <strong>hip, wrist or spine<\/strong>.<\/li>\n\n\n\n<li><strong>Fracture history due to low magnesium:<\/strong> take special care if you have had a <strong>hip, wrist or spine fracture<\/strong> associated with <strong>low magnesium<\/strong>.<\/li>\n\n\n\n<li><strong>Urinary changes:<\/strong> if you notice a <strong>decrease in urination<\/strong> or <strong>blood in your urine<\/strong>, seek medical advice.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Driving and using machines<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PEPLOC OTC <strong>may cause blurred vision or dizziness<\/strong>. Do not drive or use machinery <strong>until you know how it affects you<\/strong>.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Important ingredients<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Sodium:<\/strong> If you are on a <strong>sodium-controlled diet<\/strong>, your clinician will take this into account.<\/li>\n\n\n\n<li><strong>Mannitol:<\/strong> PEPLOC OTC contains <strong>mannitol<\/strong> and <strong>may have a laxative effect<\/strong>.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pregnancy_planning_pregnancy_and_breastfeeding\"><\/span>Pregnancy, planning pregnancy, and breastfeeding<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Not specified in the source. Speak to your doctor or pharmacist before use.<\/strong><\/li>\n\n\n\n<li>The <strong>safety in pregnancy and breastfeeding has not been established<\/strong> in the source. Do <strong>not<\/strong> take PEPLOC OTC if you are <strong>pregnant or breastfeeding<\/strong> unless advised by a health care professional.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Interactions\"><\/span>Interactions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Always tell your health care provider if you are taking any other medicines, including complementary or traditional medicines. The following medicines may be affected by, or may affect, PEPLOC OTC:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Warfarin (blood thinner):<\/strong> pantoprazole may <strong>alter the effect<\/strong>; your provider may <strong>monitor how well your blood clots<\/strong>.<\/li>\n\n\n\n<li><strong>Ketoconazole (for fungal infections):<\/strong> PEPLOC OTC may <strong>reduce absorption<\/strong>.<\/li>\n\n\n\n<li><strong>Atazanavir (anti-HIV):<\/strong> PEPLOC OTC may <strong>reduce blood levels<\/strong>; <strong>do not use<\/strong> together.<\/li>\n\n\n\n<li><strong>High-dose methotrexate (for certain cancers):<\/strong> PEPLOC OTC may <strong>increase methotrexate levels<\/strong> and <strong>lead to toxicity<\/strong>.<\/li>\n\n\n\n<li><strong>Fluvoxamine (for depression\/other psychiatric conditions):<\/strong> your doctor <strong>may reduce the dose<\/strong> if used together.<\/li>\n\n\n\n<li><strong>St John\u2019s wort (Hypericum perforatum) for mild depression:<\/strong> listed as an interacting product in the source.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Food and timing<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Take the tablet <strong>before a meal<\/strong>, <strong>preferably in the morning<\/strong>.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Antacids<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>It may take <strong>several days<\/strong> before PEPLOC OTC relieves symptoms. <strong>Antacids may be taken with PEPLOC OTC<\/strong> tablets to help with symptoms, <strong>unless<\/strong> your doctor has told you <strong>not<\/strong> to use them.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_to_take_Step-by-step\"><\/span>How to take (Step-by-step)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Check suitability:<\/strong> Ensure none of the <strong>Do not use<\/strong> conditions apply to you.<\/li>\n\n\n\n<li><strong>Dose:<\/strong> Take <strong>one 20 mg tablet once daily<\/strong>.<\/li>\n\n\n\n<li><strong>When to take:<\/strong> <strong>Before a meal<\/strong>, preferably in the <strong>morning<\/strong>.<\/li>\n\n\n\n<li><strong>How to take:<\/strong> Swallow the tablet <strong>whole with water<\/strong>. Do <strong>not<\/strong> crush, break, or chew.<\/li>\n\n\n\n<li><strong>Duration:<\/strong> Use for a <strong>maximum of 14 days<\/strong> only. If symptoms persist or worsen, <strong>see a doctor<\/strong>.<\/li>\n\n\n\n<li><strong>Antacids:<\/strong> You may <strong>use an antacid<\/strong> alongside PEPLOC OTC <strong>unless<\/strong> advised otherwise.<\/li>\n\n\n\n<li><strong>Missed dose:<\/strong>\n<ul class=\"wp-block-list\">\n<li>Take it <strong>as soon as you remember<\/strong>.<\/li>\n\n\n\n<li>If it is <strong>almost time for the next dose<\/strong>, <strong>skip<\/strong> the missed dose and take the next one at the <strong>usual time<\/strong>.<\/li>\n\n\n\n<li><strong>Do not<\/strong> take a <strong>double<\/strong> or <strong>larger<\/strong> dose to make up for a missed dose.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Overdose:<\/strong>\n<ul class=\"wp-block-list\">\n<li>If you take more than you should, <strong>contact your doctor or pharmacist<\/strong>.<\/li>\n\n\n\n<li>If they are not available, contact the <strong>nearest hospital<\/strong> or <strong>poison control centre<\/strong>.<\/li>\n\n\n\n<li>Take the <strong>leaflet<\/strong> and any <strong>remaining tablets<\/strong> with you so the clinician knows what you took.<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Note:<\/strong> Do not <strong>share<\/strong> your medicine with others.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosing_table\"><\/span>Dosing table<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Age group<\/th><th>Dose<\/th><th>Frequency<\/th><th>Maximum daily dose<\/th><th>Maximum treatment period<\/th><\/tr><\/thead><tbody><tr><td><strong>Adults<\/strong><\/td><td>20 mg<\/td><td>Once daily<\/td><td>20 mg<\/td><td><strong>14 days<\/strong><\/td><\/tr><tr><td><strong>Children<\/strong><\/td><td>Not recommended<\/td><td>\u2014<\/td><td>\u2014<\/td><td><strong>Safety and efficacy not established<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Possible_side_effects\"><\/span>Possible side effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">PEPLOC OTC can have side effects. Not all <a href=\"https:\/\/rxquora.com\/en\/donapan-tablet\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/donapan-tablet\/\">side effects<\/a> are listed here. If your <strong>general health worsens<\/strong>, or you have <strong>any unusual symptoms<\/strong>, <strong>speak to your doctor<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Serious%E2%80%94seek_urgent_help\"><\/span>Serious\u2014seek urgent help<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Stop taking PEPLOC OTC<\/strong> and seek medical attention <strong>immediately<\/strong> if you experience:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Allergic reaction:<\/strong> swelling of the <strong>hands, feet, ankles, face, lips, mouth or throat<\/strong> (which may cause difficulty <strong>swallowing or breathing<\/strong>), <strong>rash<\/strong> or <strong>itching<\/strong>.<\/li>\n\n\n\n<li><strong>Severe stomach pain<\/strong>.<\/li>\n\n\n\n<li><strong>Kidney inflammation:<\/strong> <strong>fever, rash<\/strong>, and <strong>enlarged kidneys<\/strong> sometimes with <strong>painful urination<\/strong> and <strong>lower back pain<\/strong>; this may lead to <strong>kidney failure<\/strong>.<\/li>\n\n\n\n<li><strong>Severe skin reactions:<\/strong> <strong>blistering, loosening, peeling, or redness<\/strong> of the skin, including <strong>Stevens\u2013Johnson syndrome<\/strong> (may start with <strong>flu-like symptoms<\/strong>, followed by a <strong>painful red or purplish rash<\/strong> that spreads and blisters).<\/li>\n\n\n\n<li><strong>Liver problems:<\/strong> <strong>yellow skin\/eyes<\/strong> (jaundice), <strong>black tarry stools<\/strong>.<\/li>\n\n\n\n<li><strong>Blurred vision<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Common\"><\/span>Common <span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Diarrhoea<\/strong> or <strong>constipation<\/strong><\/li>\n\n\n\n<li><strong>Abdominal pain<\/strong>, <strong>flatulence<\/strong><\/li>\n\n\n\n<li><strong>Headache<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Less_common\"><\/span>Less common <span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Low white blood cell count<\/strong><\/li>\n\n\n\n<li><strong>High concentration of fatty products in the blood<\/strong>, <strong>increased body temperature<\/strong><\/li>\n\n\n\n<li><strong>Trouble sleeping<\/strong>, <strong>depression<\/strong>, <strong>disorientation<\/strong><\/li>\n\n\n\n<li><strong>Dizziness<\/strong>, <strong>distorted taste<\/strong> or <strong>loss of taste<\/strong><\/li>\n\n\n\n<li><strong>Nausea\/vomiting<\/strong>, <strong>dry mouth<\/strong>, <strong>bloating<\/strong>, <strong>stomach pain\/discomfort<\/strong><\/li>\n\n\n\n<li><strong>Skin problems<\/strong> (other skin conditions)<\/li>\n\n\n\n<li><strong>Joint or muscle pain<\/strong>; <strong>fracture of hip, wrist, or spine<\/strong><\/li>\n\n\n\n<li><strong>Breast enlargement in men<\/strong><\/li>\n\n\n\n<li><strong>Weakness<\/strong>, <strong>fatigue<\/strong>, <strong>malaise<\/strong>, <strong>swelling of hands and feet<\/strong><\/li>\n\n\n\n<li><strong>Muscle rigidity or stiffness<\/strong><\/li>\n\n\n\n<li><strong>Acute interstitial nephritis (a type of kidney problem):<\/strong> may occur at <strong>any time<\/strong> during treatment. <strong>Call your doctor right away<\/strong> if you notice a <strong>decrease in urination<\/strong> or <strong>blood in your urine<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Other\"><\/span>Other <span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Inflammation of the large bowel<\/strong> causing <strong>persistent watery diarrhoea<\/strong><\/li>\n\n\n\n<li><strong>Low levels of salt, magnesium, or calcium<\/strong> in the blood<\/li>\n\n\n\n<li><strong>Hallucinations<\/strong>, <strong>feeling confused<\/strong><\/li>\n\n\n\n<li><strong>Tingling, prickling, \u201cpins and needles\u201d, burning, or numbness<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>What to do:<\/strong> For mild symptoms, speak to your <a href=\"https:\/\/rxquora.com\/en\/adco-contrometuses-dosage-side-effects-and-safety-tips\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/adco-contrometuses-dosage-side-effects-and-safety-tips\/\"><strong>pharmacist<\/strong> or <strong>doctor<\/strong><\/a> for advice. For symptoms listed under <strong>Serious\u2014seek urgent help<\/strong>, <strong>stop<\/strong> the medicine and <strong>get medical help immediately<\/strong>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Storage_and_disposal\"><\/span>Storage and disposal<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Keep out of reach of children.<\/strong><\/li>\n\n\n\n<li>Store at or below <strong>25 \u00b0C<\/strong>.<\/li>\n\n\n\n<li><strong>Protect from moisture.<\/strong> Keep <strong>blisters in the carton<\/strong> until required.<\/li>\n\n\n\n<li>Do <strong>not<\/strong> use after the <strong>expiry date<\/strong> printed on the label or blister.<\/li>\n\n\n\n<li><strong>Return<\/strong> any unused medicine to your <strong>pharmacist<\/strong>.<\/li>\n\n\n\n<li>Do <strong>not<\/strong> dispose of unused medicine in <strong>drains<\/strong> or <strong>sewerage systems<\/strong> (e.g., toilets).<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_the_medicine_contains\"><\/span>What the medicine contains<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Active ingredient<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pantoprazole sodium sesquihydrate<\/strong>, equivalent to <strong>20 mg pantoprazole<\/strong> per tablet.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Important excipients (core and coating)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Tablet core:<\/strong> carmellose sodium, colloidal anhydrous silica, magnesium stearate, <strong>mannitol<\/strong> (~<strong>70.50 mg per tablet<\/strong>), sodium carbonate anhydrous, sodium starch glycolate type A.<\/li>\n\n\n\n<li><strong>Tablet coating:<\/strong> hypromellose, methacrylic acid\u2013ethyl acrylate copolymer, propylene glycol, titanium dioxide, triethyl citrate, yellow iron oxide.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Notes from the source<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Contains <strong>sodium<\/strong>.<\/li>\n\n\n\n<li>Contains <strong>mannitol<\/strong> (sugar alcohol) and <strong>may have a laxative effect<\/strong>.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pack_information_and_appearance\"><\/span>Pack information and appearance<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Appearance:<\/strong><strong>orangish<\/strong>, <strong>biconvex<\/strong>, <strong>oval<\/strong>, <strong>gastro-resistant<\/strong> tablet\n<ul class=\"wp-block-list\">\n<li>Approximate dimensions: <strong>4.7 mm \u00d7 9.0 mm<\/strong><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Packs:<\/strong> supplied in <strong>aluminium\u2013polyamide-PVC\/aluminium<\/strong> blister strips; <strong>7<\/strong> or <strong>14<\/strong> tablets per carton.<\/li>\n\n\n\n<li><strong>Scheduling status (South Africa):<\/strong> <strong>S2<\/strong><\/li>\n\n\n\n<li><strong>Holder of Certificate of Registration:<\/strong> <strong>Pharma Dynamics (Pty) Ltd<\/strong><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Practical_FAQs\"><\/span>Practical FAQs <span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q1. What is PEPLOC OTC used for?<\/strong><br>It provides <strong>temporary short-term relief of heartburn and hyperacidity<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q2. How long can I take it?<\/strong><br>Use <strong>one 20 mg tablet once daily<\/strong> for <strong>up to 14 days<\/strong>. If symptoms <strong>worsen<\/strong> or do <strong>not improve<\/strong> after <strong>14 days<\/strong>, <strong>see a doctor<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q3. When should I take the tablet?<\/strong><br>Take it <strong>before a meal<\/strong>, <strong>preferably in the morning<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q4. Can I use an antacid as well?<\/strong><br>Yes. <strong>Antacids may be taken<\/strong> with PEPLOC OTC tablets <strong>unless<\/strong> your doctor has told you <strong>not<\/strong> to use them.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q5. Can children take PEPLOC OTC?<\/strong><br>No. <strong>Safety and efficacy in children have not been established<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q6. Can I use it if I am pregnant or breastfeeding?<\/strong><br>The <strong>safety is not established<\/strong> in the source. <strong>Do not<\/strong> take PEPLOC OTC if you are <strong>pregnant or breastfeeding<\/strong> unless your health care professional advises otherwise.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q7. Is it safe to drive after taking it?<\/strong><br>PEPLOC OTC may cause <a href=\"https:\/\/rxquora.com\/en\/\" data-type=\"link\" data-id=\"https:\/\/rxquora.com\/en\/\"><strong>blurred vision<\/strong> or <strong>dizziness<\/strong><\/a>. Do <strong>not<\/strong> drive or use machinery <strong>until you know how it affects you<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q8. Does PEPLOC OTC interact with other medicines?<\/strong><br>Yes. It can <strong>interact<\/strong> with <strong>warfarin<\/strong>, <strong>ketoconazole<\/strong>, <strong>atazanavir<\/strong> (do <strong>not<\/strong> use together), <strong>high-dose methotrexate<\/strong>, <strong>fluvoxamine<\/strong>, and <strong>St John\u2019s wort<\/strong> (as listed in the source). Always <strong>inform your health care provider<\/strong> about all medicines you take.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q9. What if I forget a dose?<\/strong><br>Take it <strong>as soon as you remember<\/strong>. If it is <strong>almost time<\/strong> for your next dose, <strong>skip<\/strong> the missed dose. Do <strong>not<\/strong> take a <strong>double dose<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q10. Does it contain any sugars or sodium?<\/strong><br>The tablet <strong>contains sodium<\/strong> and <strong>mannitol<\/strong> (a <strong>sugar alcohol<\/strong>, about <strong>70.50 mg per tablet<\/strong>). Mannitol <strong>may have a laxative effect<\/strong>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It is an acid-reducing medicine in tablet form. It is scheduled as S2 in South Africa and is supplied without a doctor\u2019s prescription for short-term, temporary relief of heartburn and hyperacidity. Treatment is limited to one 20 mg tablet once daily for a maximum of 14 days. If your symptoms persist or get worse, you &#8230; <a title=\"PEPLOC OTC:Uses,Side Effects,Warnings,Precautions\" class=\"read-more\" href=\"https:\/\/rxquora.com\/en\/peploc-otc-uses-side-effects-warnings-precautions\/\" aria-label=\"Read more about PEPLOC OTC:Uses,Side Effects,Warnings,Precautions\">Read more<\/a><\/p>\n","protected":false},"author":4,"featured_media":2480,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[],"class_list":["post-2084","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-package-inserts-and-medicines"],"_links":{"self":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/posts\/2084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/comments?post=2084"}],"version-history":[{"count":0,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/posts\/2084\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/media\/2480"}],"wp:attachment":[{"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/media?parent=2084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/categories?post=2084"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rxquora.com\/en\/wp-json\/wp\/v2\/tags?post=2084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}