Reydin:Uses, Side Effects, Precautions, and More

REYDIN is a prescription medicine used to treat Human Immunodeficiency Virus-1 (HIV-1) in adults over 18 years of age. It contains three active ingredients:

• Lamivudine (300 mg)
• Tenofovir Disoproxil Fumarate (300 mg)
• Dolutegravir (50 mg)

This combination works to lower the viral load in the body and improve immune function.

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Who Should NOT Take REYDIN?

You should avoid REYDIN if you:

• Are allergic to any of its active ingredients.
• Have kidney failure or liver disease.
• Are pregnant, breastfeeding, or planning to become pregnant.
• Are under 18 years old.
• Are taking medications for heart irregularities, diabetes, or hepatitis B.

Consult your healthcare professional if you have any concerns about taking REYDIN.

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Precautions While Taking REYDIN

It’s important to inform your doctor if you:

• Develop an allergic reaction (rash, swelling, fever, or joint pain).
• Experience changes in body fat distribution (e.g., fat loss in arms, legs, face; fat gain in upper back, neck, or chest).
• Have liver or kidney issues.
• Show signs of lactic acidosis (nausea, vomiting, weakness, or rapid breathing).
• Experience symptoms of pancreatitis (severe stomach pain, nausea, vomiting).
• Have osteoporosis or bone issues.

Your doctor may monitor you regularly to check for potential side effects.

Possible Drug Interactions

Some medications can interfere with REYDIN’s effectiveness or cause adverse effects. Inform your doctor if you are taking:

Medication Type	Examples	Effect on REYDIN
HIV Medications	Efavirenz, Nevirapine, Ritonavir	Decreases REYDIN levels
Heart Medications	Dofetilide, Pilsicainide	Increases toxicity risk
Diabetes Medication	Metformin	REYDIN increases its levels in the blood
Antibiotics	Vancomycin, Gentamicin	May cause kidney toxicity
Tuberculosis Drugs	Rifampicin, Isoniazid	Reduces REYDIN effectiveness
Stomach Acid Reducers	Magnesium, Calcium, Aluminium antacids	Reduce REYDIN absorption

Important Note: If taking antacids, take REYDIN two hours before or six hours after consuming them.

How to Take REYDIN

• Take one tablet daily, with or without food.
• Always follow your doctor’s instructions.
• Do not stop taking REYDIN without consulting your doctor.
• If you miss a dose, do not take a double dose to make up for it.

Possible Side Effects

Some people may experience mild to severe side effects. Contact your doctor if you notice any unusual symptoms.

Serious Side Effects (Seek Medical Help Immediately)

• Allergic reaction (swelling, rash, difficulty breathing).
• Jaundice (yellowing of skin or eyes).
• Severe liver problems (nausea, dark urine, stomach pain).
• Lactic acidosis (rapid breathing, fatigue, nausea).
• Pancreatitis (severe stomach pain, vomiting).

Common Side Effects

Category	Symptoms
General	Fatigue, fever, lack of energy
Gastrointestinal	Nausea, vomiting, diarrhea, stomach pain
Skin & Hair	Rash, itching, hair loss
Nervous System	Headache, dizziness, abnormal dreams
Muscle & Bone	Joint pain, muscle weakness, bone softening

If side effects persist or worsen, consult your healthcare professional.

Storage and Disposal

• Store below 30°C (86°F) in a tightly closed container.
• Keep away from moisture (do not store in a bathroom).
• Dispose of unused medicine responsibly—ask your pharmacist for guidance.

Reminder: REYDIN does not cure HIV or prevent its transmission. Continue using safe practices, such as condoms and not sharing needles, to reduce the risk of spreading the virus.

For any concerns or questions, always consult your doctor or pharmacist before making changes to your medication routine.